Tyypilliset lähdeverkon kuormitustallennussovellukset

(PDF) A Model of Dendritic Cell Therapy for Melanoma

PDF | Dendritic cells are a promising immunotherapy tool for boosting an individual''s antigen-specific immune response to cancer. We develop a... | Find, read and cite all the research you need on ...

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"A Validated Mathematical Model of Cell-Mediated Immune

Mathematical models of tumor-immune interactions provide an analytic framework in which to address specific questions about tumor-immune dynamics. We present a new mathematical model that describes tumor-immune interactions, focusing on the role of natural killer (NK) and CD8+ T cells in tumor surveillance, with the goal of understanding the dynamics of immune …

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Inhibition de l''angiogenèse tumorale : criblage d''une …

Au cours des dernières années, des thérapies anti-cancéreuses ciblant l''angiogenèse tumorale ont été développées et ont démontré un bénéfice en terme de survie globale pour les patients atteints de certains cancers métastatiques. Cependant, dans de nombreux cas, les tumeurs acquièrent des résistances échappent au traitement. Le développement de nouveaux …

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A cellular automata model of tumor–immune system interactions

A number of mathematical models also have coupled tumor growth with immune system dynamics. Usually, these models are fully deterministic, comprised of a series of ordinary or partial differential equations (ODEs or PDEs) describing the dynamics of, for example, tumor cells, host cells, and immune cells (Arciero et al., 2004, Bellomo et al., 1999, Bellomo and …

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Vieux amis et nouveaux venus dans la voie de ...

La voie de signalisation communément appelée voie RTK/RAS/ERK est une voie de communication intercellulaire centrale qui relaie des informations de prolifération et de différenciation en provenance de récepteurs membranaires nommés récepteurs à activité Tyrosine Kinase (RTKs) vers la petite protéine G nommée RAS qui transmet à son tour …

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D-limonene exhibits anti-inflammatory and antioxidant ...

D-limonene has been demonstrated to have important immunomodulatory properties, including antitumor effects, and may alleviate asthma and allergies. In the present study, the anti‑inflammatory effects of D‑limonene were investigated in an ulcerative colitis (UC) rat model. Healthy male Sprague‑Dawle …

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Lastuavan€työstön€elementtimallintaminen€– sovellukset

Lastuamisen€ elementtimallintamisen€ tyypilliset€ tutkimuskohteet€ ovat€ lastuamis voimat,€lastuamislämpötilat,€lastun€ja€terän€välinen€kitka,€terän€kuluminen,€lastut …

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Mixed immunotherapy and chemotherapy of tumors: Modeling, …

Request PDF | Mixed immunotherapy and chemotherapy of tumors: Modeling, applications and biological interpretations | We develop and analyze a mathematical model, in the form of a system of ...

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Dokumentit

Dokumenttien arviointi tiedon lähteenä. Sisältöjen ja käytön analyysi. Lupa tutkimiseen. Ihmisten elämästä, yhteiskunnasta ja kulttuurista voi saada tietoa monenlaisista teksteistä ja kuvista, …

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A cellular automata model of tumor-immune system interactions

There is a vast amount of literature on the use of CA to model tumor growth dynamics. Some examples include avascular tumor growth models with the CA system modelling reaction-diffusion equations ...

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Combination of ERK and autophagy inhibition as a treatment

Pancreatic ductal adenocarcinoma (PDAC) is characterized by KRAS- and autophagy-dependent tumorigenic growth, but the role of KRAS in supporting autophagy has not been established. We show that, to our surprise, suppression of KRAS increased autophagic flux, as did pharmacological inhibition of its …

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Kuormituksen tasaaminen – Wikipedia

Kuormituksen tasaaminen (engl. load balancing) on tietotekniikassa käytetty termi, jolla tarkoitetaan vaadittavan työmäärän jakamista kahdelle tai useammalle palvelimelle. Kuormituksen tasaamisessa on tarkoitukseen määritelty liikenteen jakaja, joka reitittää pyynnöt ja tehtävät palvelimille. Tyypilliset käyttökohteet on DNS-nimipalvelussa ja verkkosivujen jakamisessa.

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Tutkimusaineistojen elinkaarisuunnittelu

Viittaustiedoissa tulee mainita vähintään tekijä, aineiston nimi, julkaisuvuosi, julkaisija, versio ja saatavuustiedot eli datan pysyvä tunniste. Huomaa, että useilla arkistoilla …

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Mathematical Model Creation for Cancer Chemo-Immunotherapy

One of the most challenging tasks in constructing a mathematical model of cancer treatment is the calculation of biological parameters from empirical data. This task becomes increasingly difficult if a model involves several cell populations and treatment modalities. A sophisticated model constructed by de Pillis et al., Mixed immunotherapy and chemotherapy of tumours: Modelling, …

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Mixed immunotherapy and chemotherapy of tumors: modeling, …

We develop and analyze a mathematical model, in the form of a system of ordinary differential equations (ODEs), governing cancer growth on a cell population level with combination immune, vaccine and chemotherapy treatments. We characterize the ODE system dynamics by locating equilibrium points, determining stability properties, performing a …

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[PDF] A Validated Mathematical Model of Cell ...

A new mathematical model that describes tumor-immune interactions, focusing on the role of natural killer and CD8+ T cells in tumor surveillance, is presented, with the goal of understanding the dynamics of immune-mediated tumor rejection. Mathematical models of tumor-immune interactions provide an analytic framework in which to address specific questions …

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KvaliMOTV

Kvantifiointi toimii oivallisena apuna tyypittelyssä, koska laskelmien tai taulukoiden avulla voidaan helposti tarkastaa, ovatko kaikki tyypilliset elementit mukana konstruoitavassa kertomuksessa. …

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Lähdeviitteet eli tekstiviitteet

Lähdeviite on pieni pätkä informaatiota, jonka avulla lukija löytää tekstin lopusta olevasta lähdeluettelosta tekstissä käytetystä lähteestä täydemmät tiedot. Huomaa, että …

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Spatial Tumor‐Immune Modeling

Spatial tumor-immune modeling L. G. DE PILLIS†*, D. G. MALLET‡§ and A. E. RADUNSKAYA{# †Department of Mathematics, Harvey Mudd College, Claremont, CA 91711, USA

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(PDF) Oncolytic potency and reduced virus tumor-specificity in ...

PDF | In the present paper, we address by means of mathematical modeling the following main question: How can oncolytic virus infection of some normal... | Find, read and cite all the research you ...

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[PDF] A mathematical tumor model with immune resistance and …

By the end of the treatment period, total tumor size is smaller than that achieved through traditional pulsed therapy, and the normal cell population suffers nearly no oscillations. We present a competition model of cancer tumor growth that includes both the immune system response and drug therapy. This is a four-population model that includes tumor cells, host …

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The dynamics of an optimally controlled tumor model: A case study

DOI: 10.1016/S0895-7177(03)00133-X Corpus ID: 119422657; The dynamics of an optimally controlled tumor model: A case study @article{Pillis2003TheDO, title={The dynamics of an optimally controlled tumor model: A case study}, author={Lisette G. de Pillis and Ami Radunskaya}, journal={Mathematical and Computer Modelling}, year={2003}, volume={37}, …

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A mathematical model of immune response to tumor invasion

A mathematical model is developed to describe the process of adoptive cellular immunotherapy (ACI) using the scheme of Rosenberg and other investigators and elucidates explicitly the effects of time delays, effector immunocyte-to-tumour cell ratio, tumour growth parameters, and other critical variables on the prognosis and the therapeutic efficacy of adoptive Cellular …

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Aineiston kuvailu ja metadata

Tutkimusaineiston sisällön, keruun ja muuttujien huolellinen kuvailu on edellytys aineiston käyttökelpoisuuden säilymiselle. Ilman kuvailevaa tietoa eli metadataa tutkimusaineisto on vain …

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